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Deadlock›Heroes›Vyper
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Vyper Build Guide: Best Items & Ability Order

Slither in and assassinate enemies
OverviewHeroesItems

Vyper – Slither in and assassinate enemies. Over the last 14 days Vyper sits in D tier with a 46.1% win rate across 317.6K matches, ranked 34 of 44 heroes. In Oracle+ lobbies the win rate is 52.6%. The most common mid-game purchases are Burst Fire, Quicksilver Reload and Split Shot.

Tier
D
Win rate
46.1%
Change
−0.5%
Pick rate
13.9%
K/D/A
7.3 / 7.9 / 9.8
Avg. souls
39.9K

Vyper item build

The items players buy most in each phase. The percentage is how often the item is bought in that phase; the number below is the win rate when bought.

Early game (0–10 min)

  • I
    Close Quarters
    78%
    47.0%
  • I
    Rapid Rounds
    61%
    46.7%
  • I
    Extra Spirit
    55%
    46.1%
  • I
    Grit
    32%
    46.6%
  • I
    Extra Regen
    29%
    45.5%
  • II
    Improved Spirit
    26%
    47.6%
  • II
    Swift Striker
    22%
    46.7%
  • II
    Quicksilver Reload
    21%
    49.9%

Mid game (10–20 min)

  • III
    Burst Fire
    57%
    48.5%
  • II
    Quicksilver Reload
    38%
    47.1%
  • II
    Split Shot
    35%
    46.1%
  • III
    Tesla Bullets
    31%
    47.7%
  • II
    Bullet Lifesteal
    28%
    46.8%
  • I
    Extra Stamina
    20%
    47.3%
  • II
    Swift Striker
    18%
    45.5%
  • III
    Stamina Mastery
    17%
    51.3%

Late game (20+ min)

  • IV
    Mercurial Magnum
    52%
    48.9%
  • III
    Stamina Mastery
    31%
    45.5%
  • IV
    Ricochet
    29%
    53.5%
  • IV
    Vampiric Burst
    25%
    52.9%
  • III
    Burst Fire
    24%
    43.5%
  • III
    Point Blank
    24%
    46.6%
  • III
    Spirit Resilience
    20%
    47.4%
  • II
    Bullet Lifesteal
    19%
    47.4%

Vyper abilities

Ability 1

Screwjab Dagger

Throw a dagger, dealing spirit damage and applying slow.

Every subsequent dagger against the same target stacks in spirit damage and slow.

Damage: 50Move Speed: -28%Damage per Stack: 25Move Speed per Stack: -12%Stack Duration: 10sMax Stacks: 3Cooldown: 10sCharges: 2
  1. I

    Charges +1

  2. II

    On Hit: -8% Bullet Resist and -6% Bullet Resist per Stack

  3. III

    +2 Max Stacks -2s Charge Delay On Hit: Refund 55% Charge Cooldown

Ability 2

Lethal Venom

Inject a target with lethal venom. After a delay the venom triggers, dealing Spirit Damage. The damage is increased by the target's missing health.

Lethal Venom will ignore Petrify's damage block.

Minimum Venom Damage: 20Max Venom Damage: 140Health for Max Damage: 30%Venom Buildup Duration: 3sCooldown: 28sCast Range: 10m
  1. I

    Max Venom Damage +31.5

  2. II

    -40% Incoming Healing and -12s Cooldown

  3. III

    Bullets also build up Lethal Venom

Ability 3

Slither

You have increased Slide Distance, can Slide up hills, and can turn faster while Sliding.

Slide Distance: +15%
  1. I

    Slide Distance +20%

  2. II

    Stamina +2

  3. III

    On Slide: Gain 180 barrier for 4s

Ultimate

Petrifying Bola

Throw an explosive bola. On exploding, the bola Slows and Damages all enemies in the area.

Direct hits deal Additional Damage and Petrify instead. Petrified units block all damage, but cannot take actions.

Damage: 50Petrify Damage: 180Move Speed: -40%Slow Duration: 1.5sCooldown: 115s
  1. I

    Petrify Damage +49.5

  2. II

    Cooldown -20s

  3. III

    +1.0s Petrify Duration. Petrifies all enemies in the area.

Vyper ability order

The most common way to spend the first 12 ability points (47% of tracked players). The first point unlocks an ability, the next three upgrade it.

Screwjab Dagger123456789101112
Lethal Venom123456789101112
Slither123456789101112
Petrifying Bola123456789101112

Upgrade priority: Slither → Lethal Venom → Petrifying Bola → Screwjab Dagger

Vyper matchups and counters

Vyper's win rate when the listed hero is on the enemy team (minimum 200 matches).

Strong against

  • Pocket53.1%6.8K
  • Sinclair51.8%5.7K
  • Shiv51.4%14.3K
  • Mina51.3%19.3K
  • Rem51.0%17K

Struggles against

  • Graves38.0%23.5K
  • Paige40.7%17K
  • Seven41.5%20.3K
  • Rat King42.0%28.4K
  • Victor42.4%20.2K

Best teammates

  • Graves53.9%13.4K
  • Victor52.2%6.6K
  • Paige52.2%8.4K
  • Kelvin51.1%4.3K
  • Rat King51.0%14.6K

Frequently asked questions

Is Vyper good in Deadlock?

Vyper is currently D tier with a 46.1% win rate and 13.9% pick rate over the last 14 days. That is down 0.5% compared with the 14 days before.

What are the best items for Vyper?

Early game: Close Quarters, Rapid Rounds and Extra Spirit. Mid game: Burst Fire, Quicksilver Reload and Split Shot. Late game: Mercurial Magnum, Stamina Mastery and Ricochet. These are the items players buy most often in each phase.

What is the best ability order for Vyper?

The most common upgrade priority is Slither → Lethal Venom → Petrifying Bola → Screwjab Dagger.

Who counters Vyper?

Vyper has the lowest win rate against Graves, Paige and Seven and the highest against Pocket, Sinclair and Shiv.

Stats are calculated from matches played in the last 14 days and refreshed twice a day. Hero, ability and item details come from the game's own text. Data source: deadlock-api.com. Last updated: 2 November 2026 at 21:22. Oyunpedia is not affiliated with Valve.

Vyper
Weapon
Rapid Fire
Health
780
Move speed
6.9 m/s
Difficulty
Easy
Win rate (Oracle+)
52.6%
GunnerSlipperyRat-a-Tat

Playstyle

With a powerful weapon (and deadly venom to match), Vyper can slither into the back of teams and assassinate high-priority targets in a storm of bullets.

Lore

When it comes to breaking the law, not getting caught is a pretty important part of the job. Vyper never got that memo. Luckily for her, if there's one thing she's better at than being arrested, it's escaping out of jail.

Having done time in every major prison in the tri-state area, Vyper has built an impressive network of street level lowlifes that owe her one. She's also built an impressive network of street level lowlifes that want her dead, but she tries to focus on the positive.

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